agenda
wednesday, October 15th
8:30AM - 12:00PM
Registration Open - Location - Stone Lobby
Plenary session 4: Technological advances and drug discovery
Session Chaired by: Yuchin Albert Pan, Virginia Tech & Stephan Daetwyler, UT Southwestern
Location: Metcalf Large Ballroom
9:00AM - 9:20AM
9:20AM - 9:35AM
9:35AM - 9:50AM
9:50AM - 10:05AM
10:05AM - 10:20AM
10:20AM - 10:30AM
Invited Speaker Talk - Modeling neural development and disease with Cre/lox cell type specific knockout
Imaging of cancer cell dynamics and interactions with self-driving, multi-scale microscopy
CRISPR prime editing made precise and highly efficient by inhibition of microhomology-mediated end-joining
“Cut & Trace”: Tracking gene edited melanocyte stem cells through time
Dual Screening of Herbal Extracts with Anti-Pruritic Potential via Bio-Chip and Zebrafish Larvae-Based Assays
Flash Talks:
Comparing robotic and manual injection methods in zebrafish embryos for high-throughput RNA silencing using CRISPR-RfxCas13d
Advancing toxicology data integration through a community-led zebrafish atlas phenotype project- ZAPP
Chromosome-Level Genome Assembly of Garra rufa, a High-Temperature Tolerant Cyprinid with Biomedical Potential
From Heartbeat to Regeneration: Fast Volumetric Imaging Across Zebrafish Systems
Maura McGrail, Iowa State University, USA
Stephan Daetwyler, USA
Francois Kroll, France
Stephanie McMaster, UK
Young Sook Kim, South Korea
Jan de Sonneville, Netherlands
Alexa Burger, USA
Yasuhito Shimada, Japan
Kalliopi Arkoudi, USA
10:30AM - 11:00AM
Coffee Break
concurrent session 4a: infection and immunity 2
Session Chaired by: Jeff Yoder, NC State & Sarada Ketharnathan, CHEO
Location: Metcalf Large Ballroom
11:00AM - 11:20AM
11:20AM - 11:35AM
11:35AM - 11:50AM
11:50AM - 12:05PM
12:05PM - 12:20PM
12:20PM - 12:30PM
Invited Speaker Talk - Immunoresponsive gene 1 supports collagen remodeling during tissue repair
Holostean genomes reveal evolutionary novelty in the vertebrate immunoproteasome that have implications for MHCI function
Progranulin is a critical amplifier of the IL-6/Jak2/Stat3 pathway that controls myeloid lineage decisions
Zebrafish models of inherited bone marrow failure syndromes identify metabolic modulators that restore hematopoiesis
Development of recombinant affinity reagents for model organisms
Flash Talks:
Testing Leukemia-Essential Genes via Somatic Transgenesis and Scale Allo-Transplantation
Hepatocyte Growth Factor Is Overexpressed in AML and Remodels the Mesenchymal Stromal Cell Niche
Role of EZH2 in Developmental Hematopoiesis
Veronika Miskolci, Rutgers University, USA
Jeff Yoder, USA
Raquel Espin Palazon, USA
Sarada Ketharnathan, Canada
Robert Meijers, USA
Iman Owens, USA
Annika Chura, USA
Brittney Love, USA
concurrent session 4B: ageing and adult disease models
Session Chaired by: Daniel Cifuentes, Boston University & Vittorio Bontempi, CIBIO
Location: Conference Auditorium
11:00AM - 11:20AM
11:20AM - 11:35AM
11:35AM - 11:50AM
11:50AM - 12:05PM
12:05PM - 12:20PM
12:20PM - 12:30PM
Zebrafish as a Model to Elucidate Blood-Brain Barrier Pathophysiology and Therapeutic Opportunities in Alzheimer’s Disease
Telomere shortening triggers cGAS–STING and drives inflammation and cancer
Overexpression screen of chromosome 21 orthologs establishes erg as a potent regulator of neurodevelopment
Elucidating injury-site specific regenerative programs to rebuild the tendon
Determining the Risk of Blood Disorders in Aging LESKRES Patients Using Zebrafish Models
Flash Talks:
Mylpf dosage promotes myofibril growth in Zebrafish Fast-twitch muscle
Heterogeneity of telomere maintenance mechanisms in diffuse gliomas at the single cell level
Utilizing Donorguide for Precision Gene Editing and Disease Modeling
Caghan Kizil, USA
Giulia Allavena, France
Anna Moyer, USA
Stephanie Tsai, USA
Daniel Cifuentes, USA
Teresa Easterbrooks, USA
Vittorio Bontempi, Italy
Raeana Mayo, USA
12:30PM - 1:30PM
Lunch
Dei session
Location: Metcalf Large Ballroom
1:30PM - 1:40PM
1:40pm - 2:00pm
Flash Talks:
In vivo functional validation of missense variants underlying an ultra-rare leukoencephalopathy uncovers an evolutionary conserved role of the Endosomal Sorting Complex Required for Transport (ESCRT II)
THAP12 regulates brain development and mutations are associated with epileptic encephalopathy
Invited Speaker Talk: Beyond the Mainstream: Voices from Remote Shores in Zebrafish Research
Martina Venditti, Italy
Katarzyna Ochenkowska, Canada
Carmen Feijoo, Universidad Andrés Bello, Chile
2:30PM - 3:15PM
Excellence Award Winner
Plenary session 5: cancer biology 2
Session Chaired by: Myron Ignatius, Greehey Children's Cancer Research Institute & Vicky Tan, University of Oxford
Location: Metcalf Large Ballroom
3:15PM - 3:35PM
3:35PM - 3:50PM
3:50PM - 4:05PM
4:05PM - 4:20PM
4:20PM - 4:35PM
Invited Speaker Talk: Stress induced Apolipoprotein D modulates tumorigenic competence of melanoma
Thromboxane A2-Prostanoid Receptor (TPR) Blockade with Ifetroban Disrupts Platelet-Tumor Cell Interactions to Reduce Metastasis in Triple-Negative Breast Cancer
A Zebrafish Transplantation Screen Identifies the Sodium-Hydrogen Exchanger NHE1 as a Metabolic Vulnerability in T-cell Acute Lymphoblastic Leukemia Stem Cells
Defining the persister cell state after melanoma therapy as a BMP-dependent intrinsic property
Fishing for new immunotherapy compounds to boost innate-tumor rejection
Len Zon, Harvard Medical School, Boston Children's Hospital, Howard Hughes Medical Institute, USA
Yann Gibert, USA
Jessica Blackburn, USA
Myron Ignatius, USA
Rita Fior, Portugal
4:35PM - 5:15PM
5:30PM
6:00PM
Community Meeting and Awards - Location: Metcalf Large Ballroom
Conference Adjourns
Optional - Boston Tourism Outing (TBD)