agenda
wednesday, October 15th
8:30AM - 12:00PM
Registration Open
Plenary session 4: Technological advances and drug discovery
9:00AM - 9:20AM
9:20AM - 9:35AM
9:35AM - 9:50AM
9:50AM - 10:05AM
10:05AM - 10:20AM
10:20AM - 10:30AM
Invited Speaker Talk - Modeling neural development and disease with Cre/lox cell type specific knockout
Imaging of cancer cell dynamics and interactions with self-driving, multi-scale microscopy
CRISPR prime editing made precise and highly efficient by inhibition of microhomology-mediated end-joining
“Cut & Trace”: Tracking gene edited melanocyte stem cells through time
Dual Screening of Herbal Extracts with Anti-Pruritic Potential via Bio-Chip and Zebrafish Larvae-Based Assays
Flash Talks:
Comparing robotic and manual injection methods in zebrafish embryos for high-throughput RNA silencing using CRISPR-RfxCas13d
Advancing toxicology data integration through a community-led zebrafish atlas phenotype project- ZAPP
Chromosome-Level Genome Assembly of Garra rufa, a High-Temperature Tolerant Cyprinid with Biomedical Potential
AI-based analysis of complex pigmentation phenotypes in zebrafish embryos
Maura McGrail, Iowa State University, USA
Stephan Daetwyler, USA
Francois Kroll, France
Stephanie McMaster, UK
Young Sook Kim, South Korea
Jan de Sonneville, Netherlands
Alexa Burger, USA
Yasuhito Shimada, Japan
Heather Shive, USA
10:30AM - 11:00AM
Coffee Break
concurrent session 4a: infection and immunity 2
11:00AM - 11:20AM
11:20AM - 11:35AM
11:35AM - 11:50AM
11:50AM - 12:05PM
12:05PM - 12:20PM
12:20PM - 12:30PM
Invited Speaker Talk - Immunoresponsive gene 1 supports collagen remodeling during tissue repair
Holostean genomes reveal evolutionary novelty in the vertebrate immunoproteasome that have implications for MHCI function
Progranulin is a critical amplifier of the IL-6/Jak2/Stat3 pathway that controls myeloid lineage decisions
Zebrafish models of inherited bone marrow failure syndromes identify metabolic modulators that restore hematopoiesis
Development of recombinant affinity reagents for model organisms
Flash Talks:
Testing Leukemia-Essential Genes via Somatic Transgenesis and Scale Allo-Transplantation
Hepatocyte Growth Factor Is Overexpressed in AML and Remodels the Mesenchymal Stromal Cell Niche
Role of EZH2 in Developmental Hematopoiesis
Veronika Miskolci, Rutgers University, USA
Jeff Yoder, USA
Raquel Espin Palazon, USA
Sarada Ketharnathan, Canada
Robert Meijers, USA
Iman Owens, USA
Annika Chura, USA
Brittney Love, USA
concurrent session 4B: ageing and adult disease models
11:00AM - 11:20AM
11:20AM - 11:35AM
11:35AM - 11:50AM
11:50AM - 12:05PM
12:05PM - 12:20PM
12:20PM - 12:30PM
Invited Speaker Talk
Zebrafish as a Model to Elucidate Blood-Brain Barrier Pathophysiology and Therapeutic Opportunities in Alzheimer’s Disease
Overexpression screen of chromosome 21 orthologs establishes erg as a potent regulator of neurodevelopment
Elucidating injury-site specific regenerative programs to rebuild the tendon
Determining the Risk of Blood Disorders in Aging LESKRES Patients Using Zebrafish Models
Flash Talks:
Mylpf dosage promotes myofibril growth in Zebrafish Fast-twitch muscle
Heterogeneity of telomere maintenance mechanisms in diffuse gliomas at the single cell level
Utilizing Donorguide for Precision Gene Editing and Disease Modeling
Catarina Henriques, University of Sheffield, UK
Caghan Kizil, USA
Anna Moyer, USA
Stephanie Tsai, USA
Daniel Cifuentes, USA
Tayo Adekeye, USA
Vittorio Bontempi, Italy
Raeana Mayo, USA
12:30PM - 1:30PM
Lunch
Dei session
1:30PM - 2:30PM
Invited Speaker Talk
Carmen Feijoo, Universidad Andrés Bello, Chile
2:30PM - 3:15PM
Excellence Award Winner
Plenary session 5: cancer biology 2
3:15PM - 3:35PM
3:35PM - 3:50PM
3:50PM - 4:05PM
4:05PM - 4:20PM
4:20PM - 4:35PM
Invited Speaker Talk
Thromboxane A2-Prostanoid Receptor (TPR) Blockade with Ifetroban Disrupts Platelet-Tumor Cell Interactions to Reduce Metastasis in Triple-Negative Breast Cancer
A Zebrafish Transplantation Screen Identifies the Sodium-Hydrogen Exchanger NHE1 as a Metabolic Vulnerability in T-cell Acute Lymphoblastic Leukemia Stem Cells
Recurrent oncogenic ZC3H18 mutations stabilize endogenous retroviral RNA
Fishing for new immunotherapy compounds to boost innate-tumor rejection
Len Zon, Harvard Medical School, Boston Children's Hospital, Howard Hughes Medical Institute, USA
Yann Gilbert, USA
Jessica Blackburn, USA
Tanzina Tanu, USA
Rita Fior, Portugal
4:35PM - 5:15PM
5:30PM
6:00PM
Community Meeting and Awards
Conference Adjourns
Optional - Boston Tourism Outing (TBD)