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Institute of Clinical Physiology, National Research Council (CNR-IFC) - 4/23/2026

Position Overview

A 3-year PhD position within the PhD Programme in Genetics, Oncology and Clinical Medicine (https://genomec.dbm.unisi.it/) is available at the Oncogenomics Unit, Institute of Clinical Physiology, National Research Council (CNR-IFC) in Pisa, Italy.

BRAFV600E is a major driver of human cancer and a paradigm for targeted therapy. We identified two splicing isoforms: the canonical 220 isoform (CCDS5863) and an alternative 204 isoform (CCDS87555). These isoforms differ at their C-terminus and are consistently co-expressed in cancer cells. Both retain kinase activity and recapitulate key oncogenic features, yet experimental evidence acquired in vitro and in vivo indicates differences in tumorigenic potential.

The successful PhD candidate will use zebrafish to develop novel models aimed at comparing the oncogenic properties of BRAFV600E splicing isoforms in melanoma.

Requirements

Recent graduates in the field of Biological Sciences, Biotechnologies or similar are encouraged to apply. Candidates should:

  • Be highly motivated, self-driven, and committed to a career in science.

  • Demonstrate strong problem-solving skills (creative, critical, and open-minded thinking).

  • Be able to organize their work independently.

  • Be effective team players with a collaborative mindset toward multidisciplinary projects.

  • Be able to present and discuss data in English.

  • Have solid experience with zebrafish as a model organism (animal care and breeding, DNA extraction and genotyping, microinjection, phenotypic characterization, pharmacological treatments, xenografts).

  • Be familiar with standard molecular biology techniques (cloning, DNA/RNA extraction, PCR, qRT-PCR, Western blotting, in vitro transcription).

  • Be familiar with imaging techniques (in situ hybridization, immunofluorescence, immunohistochemistry, optical/fluorescence/confocal microscopy).

How to Apply:

If interested, please send a CV, a brief description of prior research experience, and 2–3 references to:

Laura Poliseno, PhD
Research Director
Oncogenomics Unit,
Institute of Clinical Physiology (IFC),
National Research Council (CNR)
and
Core Research Laboratory (CRL),
Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO)
Via Moruzzi 1
56124 Pisa, Italy
email: laura.poliseno@cnr.it
ORCID iD: 0000-0001-6557-955X

To view the job posting visit: Oncologia Sperimentale – Istituto di Fisiologia Clinica Cnr

Joint A*STAR - King’s College London PhD Studentships in Biomedical Science 1/16/2026

Position Overview

King’s is a research-intensive university with a global reputation for academic discovery and teaching. King’s College London and the Agency for Science, Technology and Research (A*STAR) are collaborating to offer a unique PhD experience, providing students with the opportunity to conduct research both at King’s and with an A*STAR Research Institute and Supervisor in Singapore. Up to three 4-year fully funded PhDs are available to commence in October 2026 (two studentships at UK Tuition Fees and one at International Tuition Fees). The successful candidates will have both a King’s College London and an A*STAR Supervisor.

Requirements

  • Applicants must have or be predicted to obtain a high-quality BSc degree with a 1st or a high 2:1, or a master’s qualification at Merit/Distinction grade.

  • Students recruited to these studentships must spend a minimum of 18 months and a maximum of 24 months in Singapore at an A*STAR Research Institute with the named A*STAR supervisor on each project as part of the research and training programme.

  • If English is not your first language, you will be required to provide evidence that you meet the minimum English requirements of the faculty (Band D) as prescribed by the university’s English Language requirements. If you are unable to provide this confirmation before applying any offer you are made would be conditional upon you meeting these requirements prior to enrollment and no later than the 31 of August 2026.

How to Apply:

  • Applicants must complete and submit an online admissions application, via the King’s Apply system.

  • You will need to register an account to log onto the system.

  • In addition to filling out the online application form, you will also be required to upload your CV and write a personal statement.

To view the job posting visit: Joint A*STAR—King's College London PhD Studentships in Biomedical Science | King's College London