8:30AM - 7:00PM

Registration Open - Location: Stone Lobby

9:00AM - 9:20AM

9:20AM - 9:35AM

9:35AM - 9:50AM

9:50AM - 10:05AM

10:05AM - 10:20AM

10:20AM - 10:30AM

Invited Speaker Talk - Shaping the Niche: Exploring stromal cell functions in the hematopoietic microenvironment

Dose-Dependent Regulation of Hematopoietic Development by Sfrp1a in Zebrafish

Mechanism for HSPC Expansion in the Endothelial Cuddling Niche Microenvironment through Inflammatory Lipid Mediators Receptor CysLTR1

Leveraging AHR-NLRP3 Inflammasome Axis in HSC Expansion Niche to Dissect Stress Response Driven Cell Fate Decisions

Integrated Analysis of Transcriptional and Replicative Dysregulation Reveals Candidate Drivers of MYC-Mediated Leukemogenesis

Flash Talks:

Developmental stage impacts immune responses to the bacterial PAMP ADP-heptose in larval zebrafish

PTPRJ Drives of Clonal Selection in CEBPA-mutated AML

Phosphatidylcholine Metabolism Inhibition Suppresses asxl1 Mutation Driven Clonal Hematopoiesis

Emi Murayama, Sorbonne Université, France

Mohamed Elaswad, USA

Lu Yue, USA

Morgan Walcheck, USA

Clay Foster, USA

Hanna Scholze, USA

Alexandra Lubin, UK

Brandon Gheller, USA

9:00AM - 9:20AM

9:20AM - 9:35AM

9:35AM - 9:50AM

9:50AM - 10:05AM

10:05AM - 10:20AM

10:20AM - 10:30AM

Invited Speaker Talk - Mechanism of photoreceptor degeneration and regeneration in Achromatopsia model zebrafish

Impairment of gliovascular crosstalk conserved in zebrafish, mouse and human brains drives blood-brain barrier dysfunction in Alzheimer’s disease

In vivo COL4A1/A2 syndrome models in tractable zebrafish embryos recapitulate key disease neurovascular features and contribute to uncover underlying pathomechanisms

Small molecule screen coupled with reverse genetics in a zebrafish model of progressive supranuclear palsy identify Brd4 as a regulator of microglial synaptic elimination

Targeting matrix metalloproteinase-9 attenuates changes in excitatory, but not inhibitory, synaptic expression following early-life seizures in zebrafish

Flash Talks:

Using zebrafish larvae to study haematoma clearance after intracerebral haemorrhage

A three-pronged high-throughput screen of ASD genes identifies convergent behavioral, brain activity, and transcriptomic mechanisms

Assessing BiA Toxicity in a Developing Zebrafish Model

Ichiro Masai, Okinawa Institute of Science and Technology Graduate University, Japan

Elanur Yilmaz, USA

Antonella Lauri, Italy

Edward Burton, USA

Jocelyn Lippman-Bell, USA

Abigal Bennington, UK/Ireland

Elizabeth Davidson, USA

Olivya Caballero, USA

11:00AM - 11:20AM

11:20AM - 11:35AM

11:35AM - 11:50AM

11:50AM - 12:05PM

12:05PM - 12:20PM

12:20PM - 12:30PM

Invited Speaker Talk - Autism spectrum disorder: from brain to gut

Estrogen Disrupts Hepatobiliary Architecture: Implications for Pregnancy-Associated Liver Adaptation

Lack of lysosomal master regulators tfeb and tfe3 induces pancreatitis-like defects in zebrafish

Beyond Immunity: Macrophages Help Regulate Proper Hepatic Cholesterol Metabolism

Exploring mechanisms to induce neutrophil cytotoxicity and eradicate HCC with distinct etiologies

Flash Talks:

Understanding metabolic resilience through studies in starvation-resistant cavefish

Bilirubin Mitigates Fetal Hyperglycemia-Induced Lipogenesis and Insulin Resistance by binding to and activating PPARα

Role of Macrophages in Liver Regeneration

Carine Smith, Stellenbosch University, South Africa

Patrice Delaney, USA

Alberto Rissone, USA

Matt Hamilton, USA

Juliana Gomes, USA

Jaya Krishna, USA

Madelyn Logan, USA

Manjari Trivedi, USA

11:00AM - 11:20AM

11:20AM - 11:35AM

11:35AM - 11:50AM

11:50AM - 12:05PM

12:05PM - 12:15PM

12:20PM - 12:30PM

 Invited Speaker Talk - Protecting your sense from too much pressure

Joining forces: cilia and Pkd1l1 as mechanotransducers that shape cardiac left-right asymmetry

RBFOX2 upregulation and splicing autoregulation are required for cardiomyocyte differentiation by promoting maturation of the transcriptome

Pharmacological Screens Identify Suppressors of Autism Gene-Associated Behavioral Phenotypes in Zebrafish

Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage

Flash Talks:

Elucidating the developmental mechanisms active during meningioma onset

Investigating Adhesion and Cytoskeletal Remodeling in Zebrafish Ear Morphogenesis

Complete loss of Brachyury function in zebrafish

Ian Swinburne, Berkeley, USA

Shiaulou Yuan, USA

Caroline Burns, USA

Ellen Hoffman, USA

Sizhou Huang, China

Ayyappa Raja Desingu Rajan, USA

Justine Ramos, USA

Emma Harrison, USA

2:30pm - 3:30pm

Keynote Presentation 2: Dave Langenau

Location: Metcalf Large Ballroom

3:30PM - 3:50PM

3:50PM - 4:05PM

4:05PM - 4:20PM

4:20PM - 4:35PM

Invited Speaker Talk: Systemic Inflammation Rewrites the Neutrophil Code after Injury

g3bp1-mediated stress granule formation drives melanoma initiation in zebrafish

Endothelial scavenger receptors and membrane trafficking in the trans-endothelial migration of blood stem cells

Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy

Sofia de Oliveira

Kyle Drake, USA

Gwen Beacham, USA

Deepika Dogra, Canada