agenda
Tuesday, sEPTEMBER 29TH
plenary session 5: Neuroscience & Neurological Disease Models
9:00AM - 9:20AM
Invited Speaker Talk: Predicting therapeutics that renormalize zebrafish neurological disease models | Jason Rihel, UK
9:20AM - 9:32AM
Cell type specific humanization of zebrafish genes allows for the deconstruction of cellular phenotypes in neurodegenerative disease | Marcus Keatinge, UK
9:32AM - 9:44AM
An orthogonal Cro/OR3 binary system for targeted gene expression | Kazuhide Asakawa, Japan
9:44AM - 9:56AM
Impact of Hyperglycemia and Insulin Signaling on Retinal Neurovascular Integrity and Regenerative Responses in Zebrafish | Anindita Neog, USA
9:56AM - 10:08AM
A Zebrafish Model of Subcortical Critical Period Plasticity and Visual Circuit Development | John Hageter, USA
10:08AM - 10:15AM
Flash Talks
Uncovering the Molecular Mechanisms Underlying Neurological Dysfunction in ALG8-CDG | Haley Jetter, USA
PROVE-RNU: A Zebrafish Platform to Assess Pathogenic Effects of snRNA Variants | Anna Vinken, Netherlands
A zebrafish model of an inherited neurodevelopmental disorder reveals a novel mechanism of dsRNA handling by failing mitochondria following SUPV3L1-deficiency | Diogo Candeias, UK
10:15AM - 10:35AM
coffee Break
PLENARY SESSION 6: Technology, Imaging, AI & Drug Discovery
10:35AM - 10:55AM
Invited Speaker Talk: Heart Development and Regeneration | Paul Riley, UK
10:55AM - 11:07AM
Zebrafish 3D Microanatomical Atlas: A Foundational Resource for Multimodal Multiscale Imaging | Khai C Ang, USA
11:07AM - 11:19AM
Peptide-Modified Lipid Nanoparticles enhance the anti-cancer efficacy of RNA therapeutics | Ewa Snaar-Jagalska, Netherlands
11:19AM - 11:31AM
High-resolution MALDI imaging mass spectrometry workflow for zebrafish whole-body and organ-specific imaging | Jacquelyn Spathies, USA
11:31AM - 11:43AM
Novel Approach for the Treatment of IQSEC2-mediated Disease | Sahar Isa Da'as, Qatar
11:43AM - 12:00PM
Flash Talks
Automated imaging of zebrafish embryos using robotic embryo handling and light-sheet microscopy | Ethan Giles, UK
Deep learning-based robust segmentation of zebrafish embryos | Beata Filipek-Gorniok, Sweden
Deep Learning Enables Automated Quantification of Hematopoietic Stem and Progenitor Cells (HSPCs) in Zebrafish Embryos | Xavier Vesco, USA
High-throughput drug discovery using zebrafish model of cardiac sodium channelopathies | David Chiang, USA
12:00PM - 1:30PM
LUNCH
12:30PM - 1:30PM: concurrent RIG Meet Ups
AGING RIG: Presentations by:
SkinMap: A spatial atlas of zebrafish skin across anatomic space | Johana Itzel Ramos-Galguera
Senescence-mediated recruitment of macrophages in a pre-cancer model of liver cancer | Charlene Chen
A novel population health-based approach to screen for scarring genes reveals a role for LGR4 in skin repair | Oscar Pena
CANCER RIG: Presentations by:
HDAC6/HDAC8 combined targeting as a novel therapeutic strategy for Glioblastoma Multiforme: an integrative in vitro and in vivo study | Gaia Galassi
Targeting vasculogenic mimicry to treat relapsed and metastatic rhabdomyosarcoma | Joseph Wragg
Quantitative Analysis of Immune Cell Behavior Across Inflammatory Contexts | Joaquin Canton-Sandoval
Early Metastatic Dissemination in High-Risk Neuroblastoma Facilitates Divergent Genetic Evolution | Kyle Woodward
DRUG DISCOVERY RIG: Presentations by:
Identification of bioactive compounds from fungi using zebrafish embryos | Jeroen den Hartog
Neuroprotective effects of grape-derived polyphenol treatment: risk: benefit illustrated in two zebrafish larval models of neuronal loss | Kelly Ross
Assessment of K21 Drug Candidate Activity in Zebrafish NF-κB Signaling and LPS-Induced Inflammation | Timothy Pham
Uncovering the Neuro-Immune Axis and CD24 as Parallel Drivers of Innate Immune Evasion in Colorectal Cancer | Rita Fior
GI & METABOLISM RIG: Presentations by:
Lipidomic signatures of CLN8 deficiency: stage-dependent remodeling and Ceramide Sulfatide imbalance in zebrafish brain | Sara Bernardi
NAD+ metabolism in heart regeneration | Konstantinos Lekkos
Dual protective roles of hepatic macrophages in cholesterol recycling and immune surveillance in the liver | Celia Shiau
HEMATOLOGY RIG: Presentations by:
Origins of primitive erythropoiesis in zebrafish | Ondrej Svoboda
The mTOR/Eif4e1c axis controls oncogene silencing and defines a therapeutic target in myeloid leukemia | Alba Jimanez
Novel transcription factors regulating the hematopoietic niche | Maxim Marfin
Effects of GATA2 missense mutations on HSPC generation in zebrafish | Iris Peters
Human MYC Overexpression in Zebrafish Lymphoblasts Triggers Diverse Acute Lymphoblastic Leukemia Subtypes | Jose Juan Macias
INFECTION & INFLAMMATION RIG: Presentations by:
Programmed Cell Death Pathways Coordinate Neutrophil and Macrophage Clearance in Zebrafish and Are Differentially Exploited by Salmonella Typhimurium | Sylwia Tyrkalska
Development of a Zebrafish Larvae Corneal Injury Platform to Investigate Immune Cell Dynamics in Microbial Keratitis | Kelvin Cheng
Beyond the Gut: Human Norovirus Replicates in Hepatocytes and Other Liver Cells in Zebrafish Larvae | Lorane Molineaux
Expansion of proNeu drives hematopoietic bias-engaged trained immunity in zebrafish | Dahai Yang
SKELETAL SYSTEM DISEASE RIG: Presentations by:
Exploring the Role of Mohawk Homeobox A in the Musculoskeletal System | Tatjana Haitina
Combination therapy targeting HDAC8 and SIRT1 improves muscle integrity in a dmd zebrafish model | Sabrina Carbone
NBAS-associated Osteogenesis Imperfecta Zebrafish models present early-stage impaired ossification development | Sookyung Seo
PLENARY SESSION 7: Infection & Immunity II
1:30PM - 1:50PM
Invited Speaker Talk: Immune-cardiac interaction in heart regeneration revealed by comparative analyses in fish models | Ben Shih-lei Lai, Taiwan
1:50PM - 2:02PM
Estrogen Disrupts Hepatobiliary Architecture: Implications for Pregnancy-Associated Liver Adaptation | Maria Forlenza, UK
2:02PM - 2:14PM
Influenza-associated epithelial damages promote fungal invasion in a zebrafish swimbladder model of influenza-associated pulmonary aspergillosis | Steffi Goor, Belgium
2:14PM - 2:26PM
Receptor-Specific Regulation of LC3-Associated Phagocytosis During Staphylococcus aureus Infection | Bartosz Michno, Poland
2:26PM - 2:38PM
Candida spp. suppress neutrophil reactive nitrogen species to evade killing | Philip Elks, UK
2:38PM - 2:45PM
Flash Talks
Skin microbiota prime macrophage at steady state, defining their response to tissue injury | Fernanda Samira Barría Hasbún, Chile
Microbiomes established through host social behavior support pathogen virulence mitigation | Laura Desban, USA
Investigating the neuroimmune regulation of sickness behavior in zebrafish | Flavia Terumi Nakashima, Portugal
2:45pm - 3:05pm
coffee break
PLENARY SESSION 8: Haematopoiesis & Blood Disorders
3:05PM - 3:25PM
Invited Speaker Talk: From dawn to dusk-how light and the circadian clockwork calibrates antibacterial immunity to time of day. | Chris Hall, New Zealand
3:25PM - 3:37PM
Distinct dietary fatty acids encode specific myelopoietic outcomes across vertebrates | Juan Manuel Lozano-Gil, Portugal
3:37PM - 3:49PM
Embryogenic TGF- β signaling instructs lifelong HSPC clonality and immune system competence | Marta Mastrogiovanni, USA
3:49PM - 4:01PM
A molecular switch: Ro5-3335 drives hematopoietic stem cell division and clonality through distinct RUNX1 binding partners | Anne Robertson, USA
4:01PM - 4:13PM
Cooperation, not competition: Dll4 and Jag1a signaling act cooperatively to drive haematopoietic stem cell fate specification | Rui Monteiro, UK
4:13PM - 4:20PM
Flash Talks
Multi-Modal Profiling Reveals Regulatory Mechanisms Underlying MYC-Driven Leukemogenesis | Clay Foster, USA
External Modulators of Inflammatory States within the Hematopoietic Stem Cell Specification Niche | Clyde Campbell, USA
Uncovering enhancer semantics using engineering biology and single cell omics | Shipra Bhatia, USA