8:30AM - 8:00PM

9:00AM - 10:00AM

10:00AM - 10:10AM

Registration Open - Location: Stone Lobby

RIG Leaders Meeting - Location: Terrace Lounge

ECI Committee Member Meeting - Location: Conference Auditorium

Welcome Remarks

11:00AM - 11:20AM

11:20AM - 11:35AM

11:35AM - 11:50AM

11:50AM - 12:05PM

12:05PM - 12:20PM

12:20PM - 12:30PM

Invited Speaker Talk: Using zebrafish to study the immune system's impact on the microbiota composition and intestinal disease risk

The rgs12b locus regulates macrophage epithelioid transformation during tuberculous granuloma formation

Pneumolysin-dependent and independent non-canonical autophagy processes mediate host defense against pneumococcal infection

Roles of pattern recognition pathways and chemokine receptors in anti-fungal immunity and response

Chronic macrophage activation impairs muscle repair by disrupting mannose receptor associated macrophage plasticity

Flash Talks:

Legionella species establish a replicative niche in the yolk of infected zebrafish larvae

Identifying host determinants of mycobacterial granuloma neovascularization

Targeting MYCN-induced Immunosuppression in High-risk Neuroblastoma

Sylvia Brugman, Wageningen University, Netherlands

Jacob Lowy, USA

Bartosz Michno, Poland

Robert Wheeler, USA

Celia Shiau, USA

Clarisse Leseigneur, France

Brandon Thompson, USA

Steven Dang, USA

2:30PM - 2:50PM

2:50PM - 3:05PM

3:05PM - 3:20PM

3:20PM - 3:35PM

3:35PM - 3:50PM

3:50PM - 4:00PM

Cebpa heterozygous N-term mutants selectively deregulate a subset of myeloid and progenitor cells

CEBPB regulates cancer stem cell self-renewal and therapy resistance in rhabdomyosarcoma muscle cancer

Defining the persister cell state after melanoma therapy as a BMP-dependent intrinsic property

Recurrent oncogenic ZC3H18 mutations stabilize endogenous retroviral RNA

Rhabdomyosarcoma tumours undergo endothelial trans-differentiation to evade treatment

Flash Talks:

A Novel Zebrafish Model of Multifocal Disease and Spontaneous Tumor Regression in Neuroblastoma

Structure-function of rhabdomyosarcoma fusion oncoprotein in the activation of neural pathways

A Novel Zebrafish Model for Diffuse Midline Glioma (DMG)

Elspeth Payne, National Cancer Research Institute for MDS, UK

Tiffany Eng, USA

Maggie Chasse, USA

Tanzina Tanu, USA

Joseph Wragg, UK

Kyle Woodward, USA

Andrew Vontell, USA

Alice Alhajkadour, USA

2:30PM - 2:50PM

2:50PM - 3:05PM

3:05PM - 3:20PM

3:20PM - 3:35PM

3:35PM - 3:50PM

3:50PM - 4:00PM

Invited Speaker Talk: Understanding mechanisms of lymphatic disease using zebrafish

Flow-dependent endothelial remodeling and inflammation drive developmental vascular susceptibility in ldlr knockout zebrafish

Deregulated nutrient response is an Erk-modulated pathological event in zebrafish ttntv cardiomyopathy that can be repaired via inhibiting mek1, erk1, or ppp1r10

Developmental mechanisms of pericardium formation in pediatric dilated cardiomyopathy

RASopathies are associated with defects in lymphangiogenesis

Flash Talks

Using Zebrafish to Study Myosin Binding-Protein-C Structure and Modulation of Skeletal Muscle Contractility from Molecule to Organism

Aberrant PCP Signaling Impacts Hematopoietic Lineage Fate in the LPM

3D spatial organization of heterogeneous progenitors in the zebrafish heart field pre-patterns cardiovascular development

Ben Hogan, Peter MacCallum Cancer Centre, The University of Melbourne, NHMRC, Australia

Aryan Kaveh, USA

Yan Feixang, USA

Christian Mosimann, USA

Jeroen den Hertog, Netherlands

Andrew Mead, USA

Seth Jacobsen, USA

Hakan Coskun, USA

4:30PM - 4:50PM

4:50PM - 5:05PM

5:05PM - 5:20PM

5:20PM - 5:35PM

5:35PM - 5:50PM

5:50PM - 6:00PM

Memory of the caudal fin shape is imprinted during embryonic development

Expanded knock-in targeting to visualize cellular niches and stimulate pancreatic beta-cell maturation/regeneration

Immune-Cardiac Crosstalk via Nfic Regulates Cardiomyocyte Dedifferentiation and Heart Regeneration in Zebrafish

High levels of the cardiomyocyte-specific kinase Tnni3k impair zebrafish heart regeneration by promoting inflammation and fibrosis

Development of Ewing Sarcoma Through Embryonic Reprogramming of Neural Crest to Mesoderm

Flash Talks:

Larval zebrafish and medaka as twin models for studying spinal cord regeneration and scarring

Sterile inflammation plays a crucial role in the successful regeneration of adult zebrafish kidney.

Identifying the Origins of Innate Lymphoid Cells in Zebrafish Development

Sarah McMenamin, Boston College, USA

Olov Andersson, Sweden

Yu-Jen Hung, Taiwan

Miriam Fernandez-Lajarin, USA

Elena Vasileva, USA

Samuel Wattrus, USA

Olaleye Olajuyin, USA

Anastasia Nizhnik, USA